In the current study we will measure CVI as a measure of adequate analgesia in ASA 1-3 patients during elective abdominal surgery under fentanyl/sevoflurane/epidural anesthesia. We will monitor patient movement as primary correlate to CVI and cardiovascular parameters as secondary correlates (eg, cardiac output, pulse transit time, blood pressure and heart rate).
Conditions
Interventions
Sixty ASA I-III patients for elective abdominal surgery will be given an epidural catheter prior to induction. After placement of the catheter, anesthesia will be started either with the epidural anes
Sponsors
Leiden University Medical Center, dept of Anesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 18-80 years; 2. Sex: Male or female; 3. Surgery: Elective abdominal surgery lasting at least 2 hours. This includes gynecological procedures (eg., abdominal hysterectomies), urological procedures (eg., radical prostatectomies), GI-surgery (eg., colon surgery); 4. ASA status: 1, 2 or 3.
Exclusion criteria
Exclusion criteria: 1. Age: 80 years; 2. Unable to give written informed consent; 3. Pregnancy/lactation; 4. Extreme obesity: BMI > 35; 5. Perceived difficult intubation requiring muscle relaxation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will monitor patient movement and corresponding CVI & BIS values as a measure of adequate pain relief during surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Any change in cardiovascular variables. Cardiovascular monitoring will include: Pulse transit time (PTT), heart-rate, blood pressure and cardiac output as calculated from the arterial pressure pulse wave. | — |
Contacts
Public ContactAlbert Dahan
Leiden University Medical Center (LUMC), Department of Anesthesiology, P.O. Box 9600
Outcome results
None listed