Chronic Fatigue Syndrome
Conditions
Interventions
After a basline assessment patients are randomly assigned to one of three conditions. The are two treatment conditions: small group (4 patients and 1 therapist) and large group (8 patients and two the
Sponsors
Radboud University Nijmegen Medical Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1. > 18 years old; 2. Being able to speak and read Dutch; 3. Meeting the 1994 research criteria for CFS as formulated by the US Center for Diasease Control; 4. Severely fatigued (having a CIS-fatigue severity score of >=35); 5. Severely disabled (weigthed totalscore on the Sickness Impact Profile of >=700); 6. Motivated for treatment of CFS with CBT; 7. Having functioned good in groups before (self-report) and willing to follow a group treatment for CFS; 8. Given written informed consent for participation in the study.
Exclusion criteria
Exclusion criteria: 1. Patient does no meet the herefore mentioned inclusion criteria; 2. Patients is currently engaged in a legal procedure concerning disability-related financial benefits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Fatigue severity (measured with the CIS subscale fatigue severity). 2. Disabilities (measured with the SIP total score and the SF-36 subscal 'physical functioning') The CIS-f, SIP and SF-36 are used in two assessments, a baseline and a post-treatment (or post-waiting list) assessment. The change score between post-treatment and baseline of each of the treatment conditions is compared with the difference score between post-waiting list and baseline assessment of the waiting list condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Psychological distress measured with the Symptom Checklist 90 (SCL_90). | — |
Contacts
Public ContactG. Bleijenberg
University Medical Center St. Radboud, Expert Center Chronic Fatigue, P.O. Box 9011
Outcome results
None listed