Pancreatic cancer, pancreas, bile ducts
Conditions
Interventions
Standard Whipple procedure will be performed. During surgery, the near-infrared dye ICG will be injected and the pancreatic carcinoma and extra-hepatic bile ducts will be visualized non-invasively usi
Sponsors
Leiden University Medical Center (LUMC)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with pancreatic cancer eligible to undergo a curative resection; 2. Age between 18 and 80 years old.
Exclusion criteria
Exclusion criteria: 1. No History of allergy to iodine, shellfish, indocyanine green, human serum albumin and/or history of hyperthyroidism or severe renal impairment; 2. Patient pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome parameter is the number of identified pancreatic tumors. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secundary parameters are the differences in tumor-to-background ratios measured in patients that recieved different amounts of ICG. Furthermore, the fluorescence of bile ducts on different time-points after injection. Another secundary outcome parameter is the lymfatic drainage pattern of a pancreatic tumor. | — |
Contacts
Public ContactC.J.H. Velde, van de
Leiden University Medical Center (LUMC), Department of Surgical Oncology, P.O. Box 9600
Outcome results
None listed