Feasibility and pharmacokinetics of nebulized S-ketamine inhalation in healthy adults the NebuKet study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23977

Enrollment

Registered

2015-08-11

Start date

2015-08-12

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

nebulazing ketamine

Eligibility

Inclusion criteria

Inclusion criteria: men/women 18-39years BMI <30kg/m2

Exclusion criteria

Exclusion criteria: pulmonary disease, hypertensin, liver/renal disease, neurological disorders diaphragmatic hernia/pyrosis, (history of) psychiatric or neurological disease, pregnancy/lactation, allergy to study medication, (history of) illicit drug use/alcoholism; concurrent participation in another trial

Design outcomes

Primary

Measure	Time frame
safety of procedure	—

Secondary

Measure	Time frame
analgesia, pharmakinetics ans hemodynamic effects (Blood pressure, cardiac output, heart rate	—

Contacts

Public ContactAlbert Dahan

Leiden University Medical Center (LUMC), Department of Anesthesiology, P.O. Box 9600

a.dahan@lumc.nl+31 (0)71 5262301

Outcome results