Inability to belch
Conditions
Interventions
High-resolution impedance manomotry monitoring before the scheduled botox treatment
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: - Written informed consent; - Age above 18 years; - Complains of inability to belch, for at least 3 months.
Exclusion criteria
Exclusion criteria: - Previous treatment for inability to belch - History of pharyngeal or esophagal surgery or malignancies - Use of medication affecting esophageal motility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the ability of UES relaxation in response to esophageal distention caused by ingested air as assessed with stationary high-resolution impedance manometry | — |
Secondary
| Measure | Time frame |
|---|---|
| - To evaluate the number and type of belches, their association with reported symptoms and underlying mechanism as assessed with ambulatory 24-h impedance pH-monitoring. - To identify the number of transient lower esophageal relaxations (TLESRs) - To identify secondary peristalsis in reaction to ingested air - To assess esophageal motility, UES, and LES morphology (resting pressure, relaxation pressure, presence of hiatal hernia - To evaluate quality of life and symptoms of patients before and after Botox treatment - What is the role of aerofagia in patient with inability to belch? | — |
Contacts
Public ContactRenske Oude Nijhuis
Amsterdam UMC
Outcome results
None listed