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Does mindfulness heighten emotional resilience against depression? A study of gene-person-environment interactions.

Can MBCT be used to increase reward experience in daily life in people with residual depressive symptoms?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON23910
Enrollment
120
Registered
2007-10-05
Start date
2008-01-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Depression

Interventions

Mindfulness-based cognitive therapy vs. non-active control group. The experimental group receives 8 weeks of mindfulness training by an experienced trainer in addition to their normal treatment, if an

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. At least one depressive episode in past; 2. Hamilton Depression Scale >7.

Exclusion criteria

Exclusion criteria: 1. Current depressive episode; 2. Conditions that make working in a group impossible. (MBCT is given in a group of approximately 15 people).

Design outcomes

Primary

MeasureTime frame
The increase in reward experience in daily life, whereby reward experience is conceptualised as the effect of small daily life positive events on positive mood state. The Experience Sampling Method (ESM) will be used to assess reward experience before and after the intervention. ESM is a structured diary, momentary assessment technique to study subjects in their daily life. Since ESM measurements are performed 10 times a day for 6 days, there will be a maximum of 60 measurements within each subject concerning effects of positive events on positive mood state in the flow of daily life.

Secondary

MeasureTime frame
1. Association between increase in reward experience and decrease in (i) depressive symptoms and (ii) risk of relapse; 2. Association between individual variation in reward experience (and increase in reward experience) and genetic variation in polymorphisms related to the brain reward system.

Contacts

Public ContactNicole Geschwind

Maastricht University, FPN, Clinical Psychological Science, P.O. Box 616

nicole.geschwind@maastrichtuniversity.nl+31-43 - 3881487

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)