Type 2 Diabetes Mellitus
Conditions
Interventions
Subjects will be randomized into a screening group and a control group. All subjects who have been allocated to the screening group will be invited for screening which comprises a fasting plasma gluco
Sponsors
Primary Sponsor: Erasmus MC, Department of Public Health. Secondary Sponsors: GGD (Municipal Health Service) Zuid Holland Zuid and GGD Rotterdam en omsreken.
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age (40 to 74 years inclusive); 2. Waist circumference; 3. Accounting for ethnicity; 4. Women: 80 cm or higher, men: 94 cm or higher; 5. Long-term follow-up feasible; 6. No presence of other chronic diseases that makes 5-year survival unlikely.
Exclusion criteria
Exclusion criteria: Pre-existing type 1 or 2 diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Cardiovascular morbidity and mortality based on the first occurrence of a non-fatal cardiovascular event (coronary heart disease, cerebrovascular accident, and death from any other disease of the circulatory system); 2. All cause mortality. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Prevalence of unknown type 2 diabetes detected by screening; 2. Screening performance: attendance, referral and detection rates, and test characteristics; 3. Contamination rates; 4. Change over time in the level of blood parameters: glucose, lipids, glycated haemoglobin and blood pressure in diabetic subjects; 5. Change/improvement in the cardiovascular risk profile after screen-detected diabetes and comparisons with control arm; 6. Modifications in lifestyle (diet, physical activity level, smoking) in both type 2 diabetes cases and those with IFG; 7. Cost aspects. | — |
Contacts
Public ContactH.J. Koning, de
Erasmus Medical Center, Department of Public Health, P.O. Box 1738
Outcome results
None listed