Sarcopenia should be present. Patients are however admitted to the geriatric ward because of multiple problems mostly acute
Conditions
Interventions
The patients in the control group (CG) will get usual care with daily physical therapy and the patients in the intervention group (IG) will get on top NMES during 5 days on working weekdays during 60
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a patient must meet all of the following criteria: aged 70 years and older, being frail according the Groningen Frailty Indicator (GFI score >3) and they should be sarcopenic according the European Working Group On Sarcopenia-2 criteria (EWGSOP-2) based on handgrip strength (men < 27kg and women < 16kg)), appendicular skeletal muscle mass (men < 7.0 kg/l2 and women < 7.0 kg/l2) and physical function below cut-off values (Short Physical Performance Battery <9). In a study done by Sipers et all in this population 92% of the men and 67% of the women were sarcopenic.3 Inclusion and first measurement should be done within the first three days after hospitalization.
Exclusion criteria
Exclusion criteria: A potential patient will be excluded from participation in this study if he/she meets any of the following criteria: Inability to walk prior index disease or problem before hospitalization. If a patient has a terminal condition e.g. due to metastatic cancer with a limited survival time (less than 3 month). Inability to walk due to pain or palsy during hospital stay. If a patient is not instruct able. If a patient has an implantable cardioverter defibrillator (ICD) or no informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effects of NMES on top of exercise training on physical function and skeletal muscle mass in acutely ill sarcopenic hospitalized geriatric patients. Effects will be measured with the timed Chair Stand Test (t-CST), knee extension force (KEF) assessed with a handheld dynamometer ( MicroFet-2) and skeletal muscle mass of the upper leg (ul-SMM) with multifrequency bio-impedance analysis (mf-BIA). The difference in percentage of patients with changes on these parameters (t-CST, KEF and ul-SMM) in the IG compared to the patients in the CG. | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the effect of NMES on improvement of mobility assessed with the short physical performance battery (SPPB) and the occurrence of possible adverse events. The difference in percentage of patients with changes on these parameters in the IG compared to the patients in the CG. | — |
Contacts
Public ContactWalther Sipers
Zuyderland Medisch Centrum
Outcome results
None listed