von Willebrand disease hemophilia carrier post partum hemorrhage (PPH)
Conditions
Interventions
three patient reported outcome questionaires after delivery
Sponsors
University Medical Center Utrecht
Eligibility
Inclusion criteria
Inclusion criteria: -Ongoing pregnancy beyond 10 weeks after the last menstruation -Carrier of hemophilia A or B or Von Willebrand disease type 1, type 2 or type 3 -Age >18 years
Exclusion criteria
Exclusion criteria: -Another concomitant coagulation disorder that needs a deviation of the treatment advises according to the revised national guideline on the management of pregnancy in hemophilia carriers and von Willebrand disease -Use of therapeutic or intermediate dose LMWH before delivery -Inability to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of severe PPH, defined as 1000mL or more blood loss within the first 24 hours after delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of primary PPH, defined as 500mL or more blood loss within the first 24 hours after delivery The incidence of late PPH, defined as excessive vaginal blood loss between 24 hours and 12 weeks after delivery needing hospital admission Results of the PRO questionnaires | — |
Contacts
Public ContactKarin Van Galen
Heidelberglaan 100
Outcome results
None listed