SCS in Itch

The effect of spinal cord stimulation and dorsal root ganglion stimulation on histamine induced itch: an experimental pilot study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23833

Enrollment

Registered

2020-05-08

Start date

2020-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Percutaneous administration of a drop of histamine solution to an area innervated by the SCS or DRGS and simultaneous administration of a drop of histamine solution to an area not innervated by the SC

Eligibility

Inclusion criteria

Inclusion criteria: Good effect of SCS or DRGS; the area innervated by the SCS or DRGS must extend to a healthy, pain free area of skin; participants must not have objections against switching off his or her SCS or DRGS for up to one hour; age >= 18 years; no ongoing itch perception.

Exclusion criteria

Exclusion criteria: Generalized skin disorder; systemic disease associated with pruritus; complex regional pain syndrome; allergy or hypersensitivity; contra-indications for histamine administration; use of opioids; use of drugs that might potentially prevent the development of a flare.

Design outcomes

Primary

Measure	Time frame
VAS for itch.	—

Secondary

Measure	Time frame
Size of flare, character and constancy of itch.	—

Contacts

Public ContactMoustafa Badwy

Erasmus University Medical Centre

417125mb@student.eur.nl010 704 01 40

Outcome results