acute kidney injury, oliguria, anuria, fluid responsiveness, renale response, passive leg raising, stroke volume variation
Conditions
Interventions
Thirty-five patients who are admitted to the Intensive Care Unit with diuresis <0.5 ml/kg/hr after proper initial resuscitation will be measured during a passive leg raising test and subsequently a fl
Sponsors
Prof.dr. ABJ Groeneveld
Eligibility
Inclusion criteria
Inclusion criteria: - Age 21 to 80 years - Mechanically ventilated patients - Oliguria (diuresis <0.5 ml/kg/hr) after the initial resuscitation period at the ICU
Exclusion criteria
Exclusion criteria: - medical ground - ethical grounds - Loss of blood >100 ml per hour - relevant alterations in inotropic or vasopressor medication. - Use of clinically relevant diuretics (furosemide, bumetanide, hydrochlorothiazide during the research protocol) - a known medical history of significant heart failure requiring daily administration of high dose diuretics. - pulmonary edema. - pregnancy - practical drawbacks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| increase in diuresis of >10% | — |
Secondary
| Measure | Time frame |
|---|---|
| static and dynamic haemodynamic parameters and prerenal biochemical indices | — |
Contacts
Public ContactArthur Melchers
Meibergdreef 9, 1105 AZ Amsterdam, kamer M0-210
Outcome results
None listed