Diagnostic value of distention and intima-media thickness measurement for the detection of endofibrosis and a possible role of the coagulation activation potential on the development of endofibrosis.

What is the diagnostic value of distention and intima-media thickness measurement for the early detection of endofibrosis and is there a link between the development of endofibrosis an the coagulation activation potential of the blood?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON23772

Enrollment

Registered

2014-09-11

Start date

2014-10-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coagulation, Endofibrosis, Intima-Media Thickness, vessel wall

Interventions

Ultrasound of the iliacal artery Blood collection from the forearm (30mL)

Eligibility

Inclusion criteria

Inclusion criteria: Controle population: minimal 18 years old and max 35 years old - mentally capable Population with endofibrosis: - minimal 18 years old and maximal 35. - mentally capable - complaining of lower limb ischemia during exercise - confirmed endofibrosis by Magnetic Resonance Angiography.

Exclusion criteria

Exclusion criteria: All population: diagnosed with an cardiovascular disease, operation on the a. iliacal communis or a. iliacal externa, BMI > 30, <18 years old, pregnancy

Design outcomes

Primary

Measure	Time frame
Determining the IMT of the common iliac artery wall. Determining the distension of the pelvic arterial wall. Determine coagulation parameters	—

Contacts

Public ContactJelle Posthuma

Universiteitssingel 50 Room 4.330

jelle.posthuma@student.maastrichtuniversity.nl+31 (0)43 3881542

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)