Remote ischemic preconditioning Pain QST (Quantitative Sensory Testing) Geisoleerde ischemische behandeling Pijn QST (kwantitatieve sensorische testen)
Conditions
Interventions
An observational study of a double session per subject
QST will be measured before application of the pneumatic tourniquet and after 10 minutes of pneumatic tourniquet pressure. In one session the tourniquet will be inflated 50 mmHg above volunteers systo
Sponsors
drs. V.D. Linssen
Universitair Medisch Centrum Radboudumc
Afdeling Anesthesiologie
Philips van Leydenlaan 25
6525 EX Nijmegen
Postbus 9101
6500 HB Nijmegen
Nederland
Telefoon (024) 36 55653
E-mail vera.linssen@radboudumc.nl
Eligibility
Inclusion criteria
Inclusion criteria: Healthy 18 – 65 years old
Exclusion criteria
Exclusion criteria: • Cognitive malfunction • Not being able to abstain from analgesics 1 day before examination or taking analgesics regularly • Body mass index (BMI) of > 35 kg/m2 • Post-traumatic lengthy hand reconstruction on both upper extremities • Severe crushing injuries on both upper extremities • Skin grafts on both upper extremities • Pregnancy or nursing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Does ischemic preconditioning alters pain perception in healthy individuals measured with QST? | — |
Secondary
| Measure | Time frame |
|---|---|
| • Has ischemic preconditioning a different effect on pressure pain thresholds and electrical pain thresholds measured with pressure pain thresholds (PPT), electrical pain detection threshold test (EPT) and cold pain thresholds (CPT)? • How painful are 10 minutes of ischemic preconditioning using a pneumatic tourniquet 50 mmHg above volunteers SBP measured with VAS? • Is there a correlation between the score of an individual on the Pain Catastrophe Scale and pain thresholds? | — |
Contacts
Public ContactV.D. Linssen
Universitair Medisch Centrum Radboud Afdeling Anesthesiologie Postbus 9101 6500 HB Nijmegen
Outcome results
None listed