Diagnostic accuracy of the ThinPrep liquid based versus conventional cytology.

Diagnostic accuracy, adequacy and cost-effectiveness of ThinPrep method in primary screening.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23685

Enrollment

90000

Registered

2007-07-31

Start date

2003-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Cervical cancer screening

Interventions

Comparing performance of ThinPrep with conventional cytology.

Eligibility

Inclusion criteria

Inclusion criteria: Women, participating in the national cervical screening program, recruited from family practices who were randomised to experimental arm (ThinPrep) or control arm (conventional cytology).

Exclusion criteria

Exclusion criteria: N/A

Design outcomes

Primary

Measure	Time frame
1. Cost effectiveness in terms of incremental cost per additional abnormal case detected; 2. Costs per invasive cancer prevented and life years gained.	—

Secondary

Measure	Time frame
Diagnostic accuracy in terms of detection rate ratios of cervical intraepithelial neoplasia and cancer, gain in sensitivity and positive predictive value.	—

Contacts

Public ContactJ. Bulten

Radboud University Nijmegen Medical Centre Dept of Pathology PO Box 9101, huispost 824

h.bulten@pathol.umcn.nl+31 (0)24-3614323

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)