Oral cavity carcinoma
Conditions
Interventions
Directly before the start of the operation 0.4-0.8 mL ICG-nanocolloid will be injected around the primary tumor. After the therapeutic or elective neck dissection the fluorescent lymph nodes will be e
Sponsors
The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: Patients ≥ 18 years; Patients with T1-T4 oral cavity tumor; Patients scheduled for commando resection or transoral resection with a subsequent elective or therapeutic neck dissection.
Exclusion criteria
Exclusion criteria: Patients who have received prior surgical treatment or radiation therapy to the neck; Hyperthyroid or thyroidal adenoma; History of iodine allergy; Severe kidney insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lymphatic mapping of the neck in oral cavity malignancies using ICG-nanocolloid. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Analysis of lymphatic drainage of the head and neck area to determine the extension of the neck dissection. 2. Identification of the tumor draining lymph node(s). 3. In case of lymph node metastasis: Evaluation of the rerouting phenomenon. | — |
Contacts
Public ContactW. Martin C. Klop
The Netherlands Cancer Institute
Outcome results
None listed