The BLISS 4 trial

Effect of deep versus moderate neuromuscular block during sevoflurane anesthesia on intraoperative surgical conditions, hemodynamics and postoperative pain in patients undergoing laparoscopic (donor) nephrectomies

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23555

Enrollment

100

Registered

2019-06-28

Start date

2018-06-13

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

not applicable, mostly healthy individuals

Interventions

deep neuromusculair block vs moderate neuromusculair block

Eligibility

Inclusion criteria

Inclusion criteria: (i) Patients that will undergo an elective laparoscopic (donor) nephrectomy; (ii) ASA class I-III (iii) > 18 years of age; (iv) Ability to give oral and written informed consent.

Exclusion criteria

Exclusion criteria: (i) Known or suspected neuromuscular disorders impairing neuromuscular function; (ii) Allergies to muscle relaxants, anesthetics or narcotics; (iii) A (family) history of malignant hyperthermia; (iv) Women who are or may be pregnant or are currently breast feeding; (v) Renal insufficiency, as defined by serum creatinine x 2 of normal, or urine output 35 kg/m2

Design outcomes

Primary

Measure	Time frame
Leiden Surgical rating score	—

Secondary

Measure	Time frame
Hemodynamic conditions Postoperative recovery and pain Peroperative NOL values	—

Contacts

Public ContactMaarten Honing

Leids Universitair Medisch Centrum

g.h.m.honing@lumc.nl071529964038

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)