Gestational diabetes mellitus
Conditions
Interventions
All participants will receive standard care according to the current guidelines. The women in the TRE group will get the additional advice to restrict the daily period of food intake to a self-chosen
Sponsors
Amsterdam UMC
Eligibility
Inclusion criteria
Inclusion criteria: - singleton pregnancy - diagnosis of GDM (fasting plasma glucose >6.1 mmol/l or 2 hr 75g OGTT value >7.8 mmol/l) - adequate control of Dutch or English language - eating during a period of >11 hours during a typical weekday. - amenorrhea duration at time of inclusion =34 weeks
Exclusion criteria
Exclusion criteria: - pre-existing diabetes mellitus - glucocorticoid induced diabetes mellitus - non-singleton pregnancy - circadian rhythm sleep disorders as defined in the DSM-5 - shift work during pregnancy - repeatedly crossing >2 time zones during pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • average 2-hour postprandial glucose levels • average fasting glucose levels | — |
Secondary
| Measure | Time frame |
|---|---|
| • blood glucose time in range • average blood glucose • need for glucose lowering drugs • neonatal birth weight • fasting glucose 6 weeks post-partum • maternal bodyweight gain • maternal sleep quality • pregnancy complications • neonatal complications • participant satisfaction with the diet | — |
Contacts
Public ContactDion Muller
Amsterdam UMC, location AMC
Outcome results
None listed