Effects of anatomical localization of the fentanyl patch on the pharmacokinetics and pharmacodynamics of fentanyl: A randomised cross-over trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23508

Enrollment

Registered

2012-10-08

Start date

2012-10-10

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Patients will be asked to stick the fentanyl patch to the upper arm during 9 (3x3) days. Then pharmacokinetic samples will be taken. Afterwards they stick the patch to the ventral thorax and pharmacok

Eligibility

Inclusion criteria

Inclusion criteria: 1. Stable use of fentanyl patch; 2. 18 years or older; 3. Written informed consent; 4. Stable comedication.

Exclusion criteria

Exclusion criteria: 1. Fentanyl rescue medication; 2. Mentally disabled or suffering from a psychiatric disease.

Design outcomes

Primary

Measure	Time frame
AUC and clearance.	—

Secondary

Measure	Time frame
Difference in pain scale.	—

Contacts

Public ContactW.H. Oldenmenger

Erasmus Medical Center, Daniel den Hoed Cancer Center, P.O. Box 5201

w.h.oldenmenger@erasmusmc.nl+31 (0)10 4391439

Outcome results