Macrophages, monocytes and fetal growth restriction

Maternal macrophages and monocytes in umcomplicated pregnancies and fetal growth restriction

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON23444

Enrollment

Registered

2021-03-18

Start date

2021-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal growth restriction

Interventions

None

Eligibility

Inclusion criteria

Inclusion criteria: - Informed consent - 18-40 years old - Pregnant - Gestational age (GA): 36-42 weeks - Fetal growth restriction and adequate fetal growth

Exclusion criteria

Exclusion criteria: - Smoking - BMI >30 - Immune related disorders - Fever/illness within the last month - Fertility treatment (ovulation induction, intra-uterine insemination (IUI), in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI)) - Major congenital abnormalities

Design outcomes

Primary

Measure	Time frame
Differences in macrophage and monocyte numbers and phenotype in maternal blood, placenta and cord blood	—

Secondary

Measure	Time frame
Functional status of macrophages and monocytes in maternal blood, placenta and cord blood in terms of cytokine secretion and response to pro- and anti-inflammatory triggers	—

Contacts

Public ContactRomy Bezemer

UMCG

r.e.bezemer@umcg.nl0618392842

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)