Intensive Care (IC) patients, Oxygen concentrations, Hyperoxia, CABG
Conditions
Interventions
Primary:
Increase of supplemental oxygen (FiO2) from baseline level (according to PaO2) to 90%.
Secondary:
- Mandatory inspiratory hold maneuvers.
- Arm occlusion with the Rapid Cuff Inflator by a
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Mechanically ventilated adult patients admitted to the ICU after elective coronary bypass grafting surgery
Exclusion criteria
Exclusion criteria: Pregnancy - Hemodynamic instability with a baseline mean arterial pressure (MAP) 18 mm Hg and / or dependence on moderate to high dosages of inotropic drugs after admittance to the ICU - Severe arrhythmias - Intra-cardiac shunts - Symptomatic peripheral vascular disease - Symptomatic pulmonary disease - Clinically significant aortic aneurysm - Significant valvular regurgitation - Prior diagnosis of aberrant cardiovascular anatomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac output | — |
Secondary
| Measure | Time frame |
|---|---|
| Systemic blood pressure Central venous pressure Heart rate Cerebral blood flow Mean systemic filling pressure Microcirculation | — |
Contacts
Public ContactM.D. Helmerhorst
Outcome results
None listed