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Bedside testing for lower respiratory tract infections in nursing homes.

Using Point-of-care C-reactive protein to guide Antibiotic prescribing for Respiratory tract infections in Elderly nursing home residents

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON23398
Enrollment
671
Registered
2018-08-29
Start date
2018-09-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower respiratory tract infection

Interventions

A cluster randomized controlled trial (cRCT) will be conducted in NH organizations. Participating NHs will be randomized to the intervention or control group. ln the control group, care as usual is pr

Sponsors

VU University medical center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Residence at a nursing home; - Residence at a psychogeriatric, somatic, or geriatric rehabilitation department - A new diagnosis 'suspected lower respiratory tract infection'

Exclusion criteria

Exclusion criteria: - The patient no longer wishes to be treated with antibiotics in case of a lower respiratory tract infection; - Recent use of antibiotics (oral, intravenous, or intramuscular) in the week preceding the current respiratory tract infection; - Recent infection, other than a respiratory tract infection, in the week preceding the current respiratory tract infection; - The patient receives palliative or terminal care.

Design outcomes

Primary

MeasureTime frame
The central research question is whether the use of CRP POCT results in a reduction in antibiotic prescribing for NH residents with suspected LRTl, without any negative consequences for patient recovery The primary outcome is antibiotic prescribing for suspected LRTl at index consultation (yes/no).

Secondary

MeasureTime frame
Secondary research questions: 1) Associations between CRP POCT values and: a. signs and symptoms in NH patients with suspected LRTI b. antibiotic treatment (yes/no) 2) Cost-effectiveness and cost-benefit of the use of CRP POCT compared to usual care for NH patients with suspected LRTI.

Contacts

Public ContactTjarda M. Boere

Medical Faculty building, room B353

t.boere@vumc.nl020-4445371

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)