Optimale dosering voor een ruggenprik bij kortdurende operaties.

ED50 and ED90 of intrathecal 1% chloroprocaine in day-case knee arthroscopy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23383

Enrollment

Registered

2017-11-16

Start date

2018-02-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia for knee arthroscopy

Interventions

• In the first part of the study, the injected dose of chloroprocaine will be varied according to the modified up-and-down sequential allocation method (UDM) established by Dixon and Massey.14,15 The

Eligibility

Inclusion criteria

Inclusion criteria: • Scheduled elective ambulatory knee arthroscopy • Age >18 years • American Society of Anesthesiology physical status I- III

Exclusion criteria

Exclusion criteria: • Allergy to one of the trial drugs • Contraindication to neuraxial anesthesia • Previous neuropathy to the lower extremities • Pregnancy • No informed consent

Design outcomes

Primary

Measure	Time frame
Succesfull anesthesia. Anesthesia is considered successful when: 1.Complete loss of cold sensation at the L2 dermatome, AND 2.Pain is 0-2 following inflation of the tourniquet and zero upon incision 3.Pain is 0-3 during surgery	—

Secondary

Measure	Time frame
- Motor block - TNS - Urine retention - Patient satisfaction	—

Contacts

Public ContactElsbeth Wesselink

Zaans Medisch Centrum

wesselink.e@zaansmc.nl+31 756502305

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)