Cluster headache
Conditions
Interventions
Patients will be crossed-over between treatment with oxygen at a flow rate of 7 L/min and 12 L/min. Treatment will be continued until the cluster headache attack has ended or for 15 minutes.
Sponsors
Dept. of Neurology, Atrium Medical Centre, Heerlen
Eligibility
Inclusion criteria
Inclusion criteria: Cluster headache patients of at least 18 years of age, who are naïve to oxygen treatment.
Exclusion criteria
Exclusion criteria: 1. Past oxygen use; 2. Pregnancy or lactation; 3. COPD and other contraindications for oxygen; 4. Secondary cluster headache; 5. Distracting painful conditions; 6. Incapacitation to understand and sign for informed consent; 7. Patients living outside a designated insurance zone; 8. Raise of dose of prophylactic medication in first 2 days of study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference between the flow rates of 7 and 12 L/min in percentages of achievement of a painfree state after 15 minutes of treatment with oxygen, given in at least 2 attacks/day on the first 2 days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference between the flow rates of 7 and 12 L/min in percentage of attacks treated successfully, the difference between the flow rates of 7 and 12 L/min in drop in VAS score and percentages of patients preference to the flow rates of 7 and 12 L/min, in the 4 treatment periods (i.e. day 3 till 14). | — |
Contacts
Public ContactP.J. Koehler
Atrium medisch centrum Department of neurology PO Box 4446
Outcome results
None listed