FIT, screening, colorectal cancer, advanced neoplasia, bevolkingsonderzoek darmkanker, FOBT
Conditions
Interventions
n.a.
Sponsors
Academic Medical Centre
Erasmus Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Average risk persons aged 50-75 years old in the Amsterdam and Rijnmond region. We will invite all persons from the dynamic cohort of approximately 22.000 persons that were invited in the previous rounds and were originally recruited by random selection in the city population database (Gemeentelijke Basis Administratie, GBA).
Exclusion criteria
Exclusion criteria: Exclusion criteria for colonoscopy are: complete colonoscopy or CT-colonography performed within the last 2 years; severe co-morbidity (ASA IV/V); terminal disease (life-expectancy < 5 years); inability or refusal to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Participation, positivity rate, diagnostic yield and practical use for two types of FITs (OC-Sensor and FOB-Gold) | — |
Secondary
| Measure | Time frame |
|---|---|
| Participation-rate and diagnostic yield of a 4th round of biennial FIT-screening compared to previous rounds. Impact of repeated biennial FIT-screening on participation-rates (per round, in consecutive rounds and per program), as well as the yield and occurrence of interval cancers in participants and non-participants of repeated rounds. | — |
Contacts
Public ContactE.J. Grobbee
Outcome results
None listed