THE KIMONO-STUDY.

THE KIMONO-STUDY: On the development of renal injury in children with a solitary functioning kidney.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON23298

Enrollment

150

Registered

2012-12-12

Start date

2012-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

1. Gold standard GFR measurement

2. 24h blood pressure monitoring

3. Genetical studies (eg NextGen Exome sequencing, Copy Number Variation analysis)

4. Questionaires.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with an congenital or acquired solitary functioning kidney; 2. Age 0 - 21 years.

Exclusion criteria

Exclusion criteria: 1. Renal function on DMSA > 10%; 2. A solitary functioning kidney after renal transplant.

Design outcomes

Primary

Measure	Time frame
1. Proportion of children with signs of renal injury (hypertension, proteinuria, chronic kidney disease); 2. Genetic malformations (CNV, SNPs).	—

Secondary

Measure	Time frame
1. GFR; 2. Blood pressure; 3. Developmental age of renal injury; 4. General incidence; 5. Meta-analysis data.	—

Contacts

Public ContactR. Westland

Department of Pediatric Nephrology VU University Medical Center P.O. Box 7057

r.westland@vumc.nl+31 (0)20 4443148

Outcome results