Probiotics in the prevention of traveller's diarrhoea.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23250

Enrollment

800

Registered

2007-01-31

Start date

2007-01-12

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traveller's diarrhoea, TD, traveller's diarrhea, probiotics, double blind RCT, lactobacillus, bifidobacterium

Interventions

Ecologic Travel ®, a multispecies probiotic product versus a placebo. Intervention consists of one sachet probiots in powder form containing the following strains: Bifidobacterium bifidum, Lactobacill

Eligibility

Inclusion criteria

Inclusion criteria: 1. Both male and female adults (+18); 2. Travelling to high risk area's for TD (Midle east, Asia, South and Central America, North Africa); 3. Duration of travelling: min. 7 days, max. 28 days; 4. People who experienced TD before; 5. All new travellers to high risk area's

Exclusion criteria

Exclusion criteria: 1. Use of antibiotics until two weeks before leaving; 2. Use of laxatives, acid blockers and diarrhoea inhibitors; 3. Persons who already have complaints about their stomach and/or intestines; 4. IBS/IBD and stoma patients; 5. Pregnant or breastfeeding women; 6. Patients with a serious disturbed or fragile/weak immune system (according to LCR criteria); 7. Use of probiotics two weeks before start of journey; 8. Frequent traveller's to high risk area's who never had TD complaints.

Design outcomes

Primary

Measure	Time frame
1. Consistency of stools according to Bristol scale; 2. Frequency of stools.	—

Secondary

Measure	Time frame
Duration of traveller's diarrhoea	—

Contacts

Public ContactE. Dijk, van

Papaverweg 36 B

elske.vandijk@wur.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)