Positron Emission Tomography for detection of histologic transformation of indolent non-Hodgkin’s lymphoma: a pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON23241

Enrollment

Registered

2008-10-09

Start date

2008-10-15

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non Hodgkin Lymphoma

Interventions

Patients will receive two PET-scans: one with FDG tracer and one with FLT tracer. After the diagnosis and before performing both PET-scans, patients have not received any treatment. PET-scans will be

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with newly diagnosed follicular lymphoma or newly diagnosed histological transformation of follicular lymphoma proven by histological examination. 2. Ann Arbor stage at diagnosis: II, III or IV. 3. At least one lesion > 2 cm diameter. 4. After the diagnosis and before performing both PET scans they have not received any treatment. 5. Ability to remain supine for 60 min. (PET) 6. Written informed consent.

Exclusion criteria

Exclusion criteria: 1. Uncontrolled diabetes mellitus. 2. Physical inability to access PET facilities.

Design outcomes

Primary

Measure	Time frame
- Maximal Standard Uptake Value (SUVmax), SUV mean and intraindividual variability	—

Contacts

Public ContactM.J. Wondergem

VU Medical Center Department of Hematology PK 2 BR 018 P.O Box 7057

m.wondergem@vumc.nl+31 (0)20 4442604

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)