Critical Illness
Conditions
Interventions
None listed
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Admitted to the ICU of the ZGV hospital aged 18 and above, endotracheally mechanically ventilated, expected to be in ICU for more than 48 hours, expected to be in the general ward after ICU discharge.
Exclusion criteria
Exclusion criteria: Fraction of inspired oxygen >0.7, PEEP>12 cm H2O, air leaks through tubes/cuffs and/or chest drains, pneumothorax, tracheaoesophageal fistulae or subcutaneous emphysema, unavailability of the QNRG metabolic monitor, peritoneal or hemodialysis or hemofiltration up to 4 hours before/after a session or during CRRT, expected to be transferred.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare resting energy expenditure (REE), measured by indirect calorimetry, during ICU stay and post-ICU hospital stay. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare VCO2, VO2 and respiratory quotient (RQ), measured by the QNRG indirect calorimeter during ICU and post-ICU hospital stay. To compare REE measured by QNRG with the calculated REE using the VCO2-method and several other predictive equations. To associate REE and physical performance using the CPAx-score at the ICU- and hospital discharge. | — |
Contacts
Ziekenhuis Gelderse Vallei