Non-infectious uveitis for at least 3 months.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Non-infectious uveitis for at least 3 months. - Age ≥ 18 years. - Informed consent.
Exclusion criteria
Exclusion criteria: - Major eye condition preventing any VA improvement or reduction (such as end stage glaucoma, end stage corneal diseases, end stage macular degeneration). - Suspected or proven infectious uveitis. - Masquerade syndromes (such as intraocular B cell lymphoma). - Patients for whom all data of the first year since onset of their uveitis are missing. - Patients for whom, since onset of their uveitis data from a substantial period of time (> 3 years) are missing.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| - Duration and dosage of immunosuppressive medication. - Change of inflammatory activity between entry and at 12 months. - Difference between predicted and achieved VA at 12 months. - Accuracy of predicted VA. - Difference between predicted and actual inflammatory activity at 12 months. - Accuracy of predicted activity. - Complications. - VFQ-25. - Change of outcomes for individual eyes as predicted by the model during the course of the 12 months follow up. - Change of prediction model perfomance (with respect to legal driving visual acuity, low vision, legal blindness) by means of internal validation. - IOP. - OCT. - The clinician's appraisal of the influence of the predictive model information on the prescribed therapy dosages. | — |
Primary
| Measure | Time frame |
|---|---|
| Change of visual acuity between entry and 12 months. | — |
Contacts
Rotterdam Ophthalmic Institute Postbus 70030