Ageing Inactivity
Conditions
Interventions
The intervention consists of 16 weeks of twice weekly combined gait- and strength training in groups of maximally 10 subjects. Each training sessions has a duration of 1 hour. The training will be exe
Sponsors
VU University
Eligibility
Inclusion criteria
Inclusion criteria: 1. 65-75 years; 2. Male or femaie; 3. Community dwelling; 4. No active sports participation for at least 12 months. Subjects are recruited via advertisementS in local newspapers.
Exclusion criteria
Exclusion criteria: Vacscular-, neurological- or musculosceletal diseases that would interfere with the ability to walk, the use of walking aids or contra-indications for strength testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Stability of unperturbed walking (Local dynamic stability and variability of walking); 2. Stability of perturbed walking (size of deflection from normal walking pattern and speed of return to normal walking pattern); 3. Indicators of bone turnover (markers of bonedegeneration: CTx; markers of bone synthesis: osteocalcine en P1NP). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. (Changes in) quality of the heel bone (ultrasound); 2. (Changes in) systemic growth factors (e.g. IGF-1 and Myostatin); 3. (Changes in) efficiency of walking (O2/kg/m); 4. Relation between (changes in) muscle performance parameters and (changes in) stability of walking; 5. Relation between (changes in) bone turnover parameters and (changes in) muscle performance parameters. | — |
Contacts
Public ContactMarcel Toebes
Van der Boechorststraat 9
Outcome results
None listed