Megablaas, megacystis, LUTO (Lower Urinary Tract Obstructions), urethrale kleppen, urethra atresie, Urinewegobstructie
Conditions
Interventions
None
Sponsors
University Medical Center Groningen (UMCG)
Eligibility
Inclusion criteria
Inclusion criteria: Physiological singleton pregnancy in healthy women aged 18 or older, carrying a fetus without structural anomalies and capable of reading the Dutch language will be recruited at the dating scan (10-14 weeks). Moreover twenty cases referred to our Fetal Unit for fetal mild pyelectasy, defined as an anteroposterior diameter of renal pelvis between 5-10 mm, will be included in the study.
Exclusion criteria
Exclusion criteria: Incapacitated adults, maternal disease that are likely to affect the fetal growth (hypertension requiring therapy, diabetes mellitus), multiple pregnancies, the presence of fetal malformation, abnormal karyotype or any other disease at birth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Construction of reference curves for fetal bladder diameters and volume in the second and third trimester of pregnancy. . | — |
Secondary
| Measure | Time frame |
|---|---|
| The variation in the dimensions of renal pelvis in relation to the degree of bladder filling in healthy fetuses compared to 20 cases with mild pielectasy (defined as an antero-posterior renal pelvis between 5 and 10 mm) will be investigated. Moreover, we will prospectively validate both the cut-off of bladder enlargement derived from this study in 20 cases of megacystis diagnosed in subsequent years | — |
Contacts
Public ContactFederica Fontanella
UMCG - Hanzeplein 1
Outcome results
None listed