continuous glucose monitoring (continue glucose monitoring) microcirculation (microcirculatie) intensive care unit (intensive care) cardiothoracic surgery (cardiothoracale chirurgie)
Conditions
Interventions
None listed
Sponsors
P.H.J. van der Voort, MD, PhD
Onze Lieve Vrouwen Gasthuis
Oosterpark 9, 1091 AC Amsterdam, the Netherlands
Email: p.h.j.vandervoort@olvg.nl
Eligibility
Inclusion criteria
Inclusion criteria: 1. Admission to the hospital for elective open cardiac surgery (coronaty artery bypass graftl mitral-, tricuspidal- and aortic valve surgery); 2. Age 18-85 years; 3. Willing and able to give written informed consent.
Exclusion criteria
Exclusion criteria: Abdominal abnormalities that inhibit sensor insertion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in glucose values (mmol/l) measured by the two CGMs, Guardian RT and FreeStyle Navigator, compared to 'gold standard' blood glucose values measured by the Accu-Chek Compact Plus (mmol/l), expressed as mean absolute difference (MAD) of glucose values. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Microcirculatory function expressed as % of perfused vessels as measured by OPS; 2. Microcirculatory function expressed as microvascular flow index (MFI) as measured by OPS; 3. Tissue oxygen saturation (StO2) expressed as ratio oxygenated haemoglobin to total haemoglobin as measured by near infrared spectroscopy (NIRS); 4. Systemic oxygen saturation (SpO2) expressed as % as measured by pulse oximetry; 5. APACHE II score; 6. SOFA score. | — |
Contacts
Public ContactS.E. Siegelaar
Outcome results
None listed