The Staphylococcus aureus bacteria with insensitivity for methicillin antibiotics: a search for new risk factors and renewel of the guidelines / De Staphylococcus aureus bacterie met ongevoeligheid voor meticilline antibiotica: Een zoektocht naar nieuwe risicofactoren en vernieuwing van de richtlijnen.

MRSA of Unknown Origin: Risk Assessment and Adjustment of Risk Classification.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON23061

Enrollment

600

Registered

2009-10-01

Start date

2009-07-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

What are the source(s), or origin(s), mode(s) of transmission and determinants of acquisition of MRSA of Unknown Origin (MUO) found in persons without presently known risk factor for MRSA carriage as defined by the current National WIP guideline?

Interventions

None.

Eligibility

Inclusion criteria

Inclusion criteria: MRSA send by the laboratory to the RIVM. Inclusion based on being a MUO by routine questionnaire.

Exclusion criteria

Exclusion criteria: Case with (severely) incomplete background epidemiological data.

Design outcomes

Primary

Measure	Time frame
Development of a new algorithm. Implementation of the new algorithm by the HCC’s and public health. Evaluation of the algorithm is done by comparing the rate of MRSA carriers characterized as belonging to one of the defined risk groups (including new ones), to the rate of MRSA defined as MUO. If this study identified significant risk groups and implementation of this knowledge is sufficient, the risk group rate will increase over time.	—

Measure

Time frame

Development of a new algorithm. Implementation of the new algorithm by the HCC’s and public health. Evaluation of the algorithm is done by comparing the rate of MRSA carriers characterized as belonging to one of the defined risk groups (including new ones), to the rate of MRSA defined as MUO. If this study identified significant risk groups and implementation of this knowledge is sufficient, the risk group rate will increase over time.

—

Secondary

Measure	Time frame
A found difference in characteristics (phenotype, profiling, genetics) for MUO (MRSA) strains.	—

Contacts

Public ContactW.S.N. Lekkerkerk

Erasmus MC 's-Gravendijkwal 230 Postbus 2040

w.lekkerkerk@erasmusmc.nl+31 10 7033510

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)