Biologische tumorkenmerken voorspellend voor de respons op chemoradiotherapie bij slokdarmkanker

MARKERS OF RESPONSE TO CHEMORADIATION IN ESOPHAGEAL CANCER Selection and validation of a panel of markers

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON23044

Enrollment

Registered

2015-07-21

Start date

2015-09-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-metastastatic esophageal cancer niet uitgezaaid slokdarmkanker

Interventions

Staging and treatment will be performed according to local and Dutch treatment guidelines. During the regular endoscopic ultrasonography (EUS) staging procedure 4 extra biopsies for biomarker testing

Eligibility

Inclusion criteria

Inclusion criteria: All patients referred to MCL with pathologically proven carcinoma of the esophagus and without distant metastases will be asked to participate

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
The main study parameters are differences in kinetic profile and/or genetic profile between patients with and without a pathologic complete response after chemo radiation.	—

Secondary

Measure	Time frame
The association of the created predictive profile and relapse/survival outcome parameters	—

Contacts

Public ContactW.E. Fiets

Medisch Centrum Leeuwarden

058-2866660

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)