Lung cancer
Conditions
Sponsors
Medisch Spectrum Twente Enschede
Eligibility
Inclusion criteria
Inclusion criteria: Subjects suspected for lung cancer: 1. Scheduled to undergo CT-scanning; 2. They have suspicion of lung cancer based on the one or more of the following points: a. Respiratory symptoms such as: haemoptysis, coughing, dyspnoea; b. General symptoms that go with malignancy, such as: weight loss, nocturnal hyperhidrosis, fever, and/or loss of appetite; c. An anomalous chest X-ray; 3. Age ≥ 40 years; 4. Smoker or ex-smoker. Healthy subjects: 1. A negative history of chest symptoms, for example asthma, COPD, other respiratory conditions.
Exclusion criteria
Exclusion criteria: Subjects suspected for lung cancer: 1. Subjects with other prior known malignancies; 2. Subjects with a history of upper or lower respiratory tract infection during the past 4 weeks prior to measurements which required pharmacological treatment with antibiotics or systemic corticosteroids. Healthy subjects: 1. Subjects with known significant metabolic disease, such as: diabetes mellitus, liver failure or active liver disease, renal failure, haemodialysis or cardiac failure, because of possible (un)known effects on metabolism; 2. Subjects with known COPD; 3. Subjects with an underlying malignancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of differences in patterns of exhaled breath in patients diagnosed with lung cancer from subjects with a rejected diagnosis of lung cancer and healthy subjects. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Detection of different patterns of exhaled breath in different lung cancer stages. - Detection of different patterns of exhaled breath in different types of lung cancer. | — |
Contacts
Public ContactSharina Kort
Deurningerstraat 54
Outcome results
None listed