Skip to content

The impact of milk protein glycation on muscle protein synthesis after resistance training in healthy young men

The impact of milk protein glycation on muscle protein synthesis after resistance training in healthy young men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON22985
Enrollment
45
Registered
2020-06-03
Start date
2020-06-03
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

- Low-glycated milk protein + 2 grams leucine - High-glycated milk protein + 2 grams leucine - Water placebo

Sponsors

Maastricht University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Males - Aged between 18-35 years - Healthy, recreationally active (participating in recreational sports activities = 1 and = 6 h per week, with a maximum of 2 h resistance-type exercise) - 18.5 = BMI = 30 kg/m2 - No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner).

Exclusion criteria

Exclusion criteria: - Smoking - Lactose intolerant or allergies to milk proteins - Regular consumption of protein supplements (e.g. protein powders) - Musculoskeletal disorders - Metabolic disorders - Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications). - Chronic use of gastric acid suppressing medication or anti-coagulants - Recent (<9 months) participation in amino acid tracer (L-[ring-13C6]-phenylalanine and L-[3,5-2H2]-tyrosine) studies - Unstable weight over the last three months - Diagnosed GI tract disorders or diseases - Blood donation in the past 2 months

Design outcomes

Primary

MeasureTime frame
Muscle protein synthesis rates from 0-6 h following drink ingestion

Secondary

MeasureTime frame
- Muscle protein synthesis rates from 0-2 and 2-6h - Plasma lysine concentrations - Plasma amino acid concentrations

Contacts

Public ContactGlenn van Lieshout

Maastricht University

g.vanlieshout@maastrichtuniversity.nl0641381117

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)