Simultaneously right heart catheterization and echocardiography in patients with pulmonary arterial hypertension to validate the non-invasive deformation-area loop

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22967

Enrollment

Registered

2018-01-10

Start date

2018-01-15

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with pulmonary arterial hypertension (PAH)

Interventions

To create the pressure-volume changes we will use a balloon-catheter to partially obstruct the venous return in the Vena Cava inferior.

Eligibility

Inclusion criteria

Inclusion criteria: - strong suspicion of PAH, WHO group 1, confirmed during right hearth catheterization. - Over 18 years of age - voluntary

Exclusion criteria

Exclusion criteria: - cardiovascular diseases, other than PAH - diabetes mellitus

Design outcomes

Primary

Measure	Time frame
- The relation between the systolic slope of the deformation-area loop and the end-systolic pressure-volume relationship of the pressure volume curve. - The relation between the slope of the diastolic part of the deformation-area loop during passive filling and the end-diastolic pressure-volume relationship of the pressure volume curve.	—

Secondary

Measure	Time frame
Other correlation between the characteristics of the deformation-area loop and the pressure-volume curve.	—

Contacts

Public ContactHugo Hulshof

Phililps van Leijdenlaan 15

Hugo.G.Hulshof@radboudumc.nltelephone +31 (024) 3614209

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)