Prolonged muscle protein synthetic response to the ingestion of a large amount of protein

The effect of the ingestion of large amount of protein on muscle protein synthesis rates

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22927

Enrollment

Registered

2019-04-25

Start date

2019-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

0 g protein 25 g protein 100 g protein

Eligibility

Inclusion criteria

Inclusion criteria: - Male - Aged between 18-40 years - Healthy - 18.5 = BMI 30 = kg·m-2

Exclusion criteria

Exclusion criteria: - Smoking - Sports/exercise > 4 sessions/week - Lactose intolerant or allergies to milk protein - A history of neuromuscular problems - Use of anticoagulation medication - Recent (<9 months) participation in amino acid tracer (L-[ring-2H5-phenylalanine, L-[ring-2H2]-tyrosine, and [1-13C]-leucine infusion) studies - Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription acne medications). - Strict vegetarian (because of standardized Aviko meal) - Injury or condition that would limit the participant from performing the resistance exercise.

Design outcomes

Primary

Measure	Time frame
Myofibrillar protein synthesis rates	—

Secondary

Measure	Time frame
Whole-body protein kinetics and metabolism, plasma metabolites (e.g. glucose and insulin), 1-13C-phenylalanine incorporation	—

Contacts

Public ContactJorn Trommelen

Maastricht University Medical Centre+

jorn.trommelen@maastrichtuniversity.nl043-3881617

Outcome results