iron deficiency iron deficiency anaemia young healthy children from the Netherlands
Conditions
Interventions
During insertion of a peripheral intraveneus catheter, 2 cc of whole blood will be collected for analysis of the iron status. Demographic, dietary and medical information will be collected.
Sponsors
HAGA ziekenhuis / Juliana Kinderziekenhuis
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male and female subjects, aged 6-36 months undergoing elective surgery; 2. General anesthaesia induced by intravenous injection; 3. Stable health status and expected to remain stable; 4. Written informed consent from parents/guardian.
Exclusion criteria
Exclusion criteria: 1. Known infection in the last 4 weeks; 2. Oncologic disorder; 3. Acute or chronic illness; 4. Congenital malformations; 5. Chronic or inhereted metabolic disease; 6. Premature at birth (<32 weeks); 7. Hemoglobinopathies; 8. Use of iron supplementation less than 6 weeks prior to operation; 9. Blood transfusion in the last 6 months.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To define whether following factors contribute to iron deficiency during childhood: 1. Iron status at birth (maternal iron status/anaemia, smoking during pregnancy, preeclampsia, lower gestational age and lower birth weight); 2. Postnatal needs for iron (more rapid growth); 3. Bioavailable iron (more cow milk); 4. Sex; 5. Ethnicity (European versus non-European); 6. Socioeconomic status; 7. BMI; 8. Attending day-care. | — |
Primary
| Measure | Time frame |
|---|---|
| 1. Iron status; 2. Serum haemoglobin; 3. Mean cell volume and serum ferritin; 4. Reticulocyte hemoglobin content. | — |
Contacts
Public ContactLieke Uijterschout
Juliana Kinderziekenhuis Sportlaan 600
Outcome results
None listed