Colorectal carcinoma
Conditions
Interventions
Sponsors
Leiden University Medical Center, Leiden, the Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients > 18 years old; 2) Patients scheduled and eligible for resection because of colorectal carcinoma; 3) Patients should be capable and willing to give informed consent before study specific procedures; 4) Screening ECG and clinical laboratory test results are within normal limits, or if any are outside of normal limits they are considered to be clinically insignificant; 5) The patient has a normal or clinically acceptable medical history, physical examination, and vital signs findings at screening; 6) Absence of any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial.
Exclusion criteria
Exclusion criteria: Patients will be excluded if any of the criteria below apply: 1) History of a clinically significant allergy or anaphylactic reactions; 2) Patients pregnant or breastfeeding, lack of effective contraception in male or female patients with reproductive potential; 3) Any condition that the investigator considers to be potentially jeopardizing the patients well-being or the study objectives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the feasibility of cRGD-ZW800-1 to visualize tumors in real-time using dedicated NIR fluorescence imaging systems | — |
Secondary
| Measure | Time frame |
|---|---|
| To define the optimal dose of cRGD-ZW800-1 for intraoperative near-infrared fluorescence imaging of tumors. | — |
Contacts
Public ContactAlexander Vahrmeijer
LUMC
Outcome results
None listed