Adult patients (>18y), scheduled for coronary arterial bypass graft surgery and/or mono valve surgery
Conditions
Interventions
We will perform non-invasive ultrasound measurements of the carotid blood flow in ICU patients, before and after events that are expected to change preload or SVR, that may also result in change of ca
Sponsors
Amsterdam UMC location AMC
Eligibility
Inclusion criteria
Inclusion criteria: To be eligible to participate in this study, a subject must meet all of the following criteria: - Adult patient (age > 18 years) - Elective coronary arterial bypass graft surgery and/or mono valve surgery - Informed consent
Exclusion criteria
Exclusion criteria: A subject who meets any of the following criteria will be excluded from participation in this study: - Significant aortic valve stenosis > 30% without indication for valve repair, or abnormal anatomy of aortic, femoral, carotid or brachial artery 12 - Postoperative severe aortic valve regurgitation or stenosis > 30% - Atrial fibrillation or arrhythmias - Cerebrovascular accident - COPD GOLD 3 or 4 - Inability to measure carotid artery blood flow - Carotid bifurcation anatomically to low - Contra-indications for femoral arterial catheter placement (e.g., vascular graft)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the accuracy of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement and describe if the limit of agreements are between ±30%. | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the trending ability of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement. Third Objective: To compare the precision of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement. Fourth Objective: To compare the response to therapy (directional changes) of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement. Other Objectives: To study the accuracy of carotid blood flow variation measurement with ultrasound compared to invasive and non-invasive stroke volume variation measurements. | — |
Contacts
Public ContactSantino Rellum
Amsterdam UMC locatie AMC
Outcome results
None listed