Effect of early biventricular pacing on long-term left ventricular remodeling in patients with acute myocardial infarction (RESCUE-MI).

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22809

Enrollment

Registered

2008-01-16

Start date

2008-02-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Myocardial infarction

Interventions

Open-label trial in which patients will be randomly assigned to one of two groups: optimal medical treatment plus a biventricular pacemaker with implantable cardioverter-defibrillator (biventricular I

Eligibility

Inclusion criteria

Inclusion criteria: 1. Presentation with an acute MI; 2. Primary PCI as treatment for acute MI; 3. No history of ischemic heart disease; 4. Peak Troponin T >8 µg/L within 24 hours after admission; 5. LV ejection fraction <45%; 6. LV dyssynchrony ≥130ms (assessed with speckle tracking analysis); 7. At least 18 years of age.

Exclusion criteria

Exclusion criteria: 1. Malignancy or other major co-morbidity; 2. Expected non-compliance to the study protocol.

Design outcomes

Primary

Measure	Time frame
(Change in) LV end-systolic volume (LVESV) at 6 months follow-up.	—

Secondary

Measure	Time frame
Clinical status of patients at 6 months follow-up.	—

Contacts

Public ContactS.A. Mollema

Leiden University Medical Center Department of Cardiology (C5-P) Albinusdreef 2

s.a.mollema@lumc.nl071-5262020

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)