Critical Illness Polyneuromyopathy - The effect of electrical nerve stimulation.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22801

Enrollment

Registered

2008-12-10

Start date

2009-02-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness polyneuromyopathy ICU-acquired weakness Critical Illness polyneuromyopathie electrical stimulation elektrische zenuwstimulatie

Interventions

Electrical nerve stimulation of the N. peroneus communis on one leg. Randomization determines whether the dominant or non-dominant leg is stimulated. Stimulation will be applied daily for 30 minutes o

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age above 18 years; 2. aortic surgery; 3. mitral valve repair or replacement surgery; 4. double valve surgery; 5. coronary artery surgery with poor left ventricle function; 6. patients scheduled for cardiovascular surgery with chronic kidney failure or kidney-function disorders; 7. COPD patients scheduled for cardiovascular surgery with FEV1 < 1.5 Liter; 8. patients with preexisting pulmonary disorders scheduled for cardiovascular surgery; 9. admission at thoracic ICU; 10. obtained informed consent.

Exclusion criteria

Exclusion criteria: 1. Existing neuropathy or myopathy; 2. not having 4 limbs.

Design outcomes

Primary

Measure	Time frame
Difference in muscle force (percentage) between stimulated and non-stimulated legs on day 1 and day 10.	—

Secondary

Measure	Time frame
Values of electrophysiological features, such as: 1. CMAP; 2. SNAP; 3. conduction velocity; 4. MUAPs; 5. spontaneous EMG acitivity; 6. direct muscle stimulation (DMS).	—

Contacts

Public ContactJ Vermeijden

Haaksbergerstraat 55

j.vermeijden@ziekenhuis-mst.nl+31 (0)534872000

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)