Do patients with type 2 diabetes need to exercise in fasting condition to improve glucose regulation?

Exercise training in the fasted vs. postprandial state to augment the clinical benefits of long-term in exercise intervention in type 2 diabetes patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22795

Enrollment

Registered

2014-07-31

Start date

2014-08-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Subjects are randomly assigned, by envelope, to three months of exercise training in the fasted state (before breakfast) (n=20) or postprandial state (after breakfast) (n=20). At entry of intervention

Eligibility

Inclusion criteria

Inclusion criteria: Fifty T2DM patients (HbA1c 6.5-9.0%) will be included in a randomized trial. Subjects with following characteristics will be included: male, age 40-75 years, sedentary (<2 hours sport/week), treated by oral blood glucose lowering medication.

Exclusion criteria

Exclusion criteria: Exogenous insulin therapy or clopidogrel treatment, history of coronary events/revascularization (PCI, CABG, and/or AMI), presence of chronic pulmonary, renal disease and/or orthopedic disease that interferes with exercise training, involvement in exercise training and/or caloric restriction program for at least one year.

Design outcomes

Primary

Measure	Time frame
Insulin sensitivity and glycemic control.	—

Secondary

Measure	Time frame
Exercise capacity, metabolic flexibility, body composition, muscel fibre characteristics.	—

Contacts

Public ContactD. Hansen

Maastricht University

dominique.hansen@maastrichtuniversity.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)