eating behaviour
Conditions
Interventions
Oral and gastric stimulation:
Subjects receive (after inclusion, IC and training session) 5 treatments. 4 treatments with 2x2 design with:
1. Oral stimulation: 1 min or 8min modified sham feeding
2. Gastric stimulation: Infusion of 500ml of liquid with 100kcal or 700kcal into the stomach with a naso-gastric tube.
Besides these 4 treatments there is a control condition: No oral stimulation but
Sponsors
Wageningen University, Division of Human Nutrition
Eligibility
Inclusion criteria
Inclusion criteria: 1. Gender: male; 2. Age: 18 - 40 y; 3. BMI: 18.5 - 25.0 kg/m2; 4. Stable body weight (change of <5kg in the last 2 months); 5. Healthy: as judged by the participant; 6. Having signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Smoking or drug abuse; 2. Gastro-intestinal diseases; 3. Diabetes, thyroid diseases or any other endocrine disorders; 4. Lack of appetite for any reason; 5. Hypersensitivity or food allergy for products used in this study; 6. Currently participating in another clinical trial or planning to start participation during this study; 7. Taking any medication, except for light pain relieving medications which are available over the counter (acetylsalicylic acid or paracetamol); 8. Problems with the respiratory tract, such as hyperventilation, asthma or bronchitis, which can cause problems when the naso-gastric tube is inserted; 9. Working at, or doing an MSc. thesis at the Division of Human Nutrition of Wageninen University.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the effect of short/long oro-sensory exposure combined with a gastric load low/high in energy, on the rate of gastric emptying. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the effect of short/long oro-sensory exposure combined with a gastric load low/high in energy, on subjective feelings of satiety; | — |
Contacts
Public ContactAnne Wijlens
PO Box 8129
Outcome results
None listed