Liver cancer, Liver tumor, colorectal liver metastases, hepatocellular carcinoma.
Conditions
Interventions
Standard liver resection will be performed. After mobilization, the near-infrared dye ICG will be injected i.v. and liver tumors will be visualized non-invasively and using our experimental camerasyst
Sponsors
Leiden University Medical Center (LUMC)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with colorectal cancer liver metastasis or hepatocellular carcinoma that are eligible for resection; 2. Age between 18 and 80 years old.
Exclusion criteria
Exclusion criteria: 1. No history of allergy to iodine, shellfish, indocyanine green, human serum albumin and/or history of hyperthyroidism or severe renal impairment; 2. Patient pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intra-operative identification rate, defined as the number of tumours that were identified with the fluorescent signal of ICG during operation, compared with the number of microscopically confirmed tumours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor to background ratio between different doses of ICG injected and different time intervals injected. | — |
Contacts
Public ContactC.J.H. Velde, van de
Leiden University Medical Center (LUMC), Department of Surgical Oncology, P.O. Box 9600
Outcome results
None listed