Platelet function disorders Trombocytopathie
Conditions
Interventions
None
Sponsors
UMC Utrecht
Eligibility
Inclusion criteria
Inclusion criteria: - Age > 18 years - History of bleeding diathesis suspected for a PFD
Exclusion criteria
Exclusion criteria: - Inability to give informed consent - Bleeding diathesis due to an acquired PFD, von Willebrand disease, hemophilia or other disorders of secondary hemostasis or fibrinolysis - Current use of antiplatelet therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Frequency and severity of bleeding symptoms: bleeding score using the ISTH-BAT - Treatment of bleeding diathesis: type and frequency of treatment received in the past (local treatment, antifibrinolytics, DDAVP, platelet transfusion) - Impact of PFD on quality of life: RAND-36 health survey score | — |
Secondary
| Measure | Time frame |
|---|---|
| - Diagnostic utility of additional platelet tests as compared to standard LTA - Relation between type of PFD and bleeding phenotype - Genotype-phenotype relationship | — |
Contacts
Public ContactMaaike Blaauwgeers
Van Creveldkliniek UMC Utrecht - huispost C01.425
Outcome results
None listed