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The effect of continuation of anti-platelet agents on bleeding complications after dento-alveolar surgical procedures.

The effect of continuation of anti-platelet agents on bleeding complications after dento-alveolar surgical procedures.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON22690
Enrollment
145
Registered
2006-02-07
Start date
2005-09-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

caries, parodontitis apicalis, adult parodon titis

Interventions

Continuation of anti-platelet agents during the ten days prior to the procedure.

Sponsors

Academic Medical Center, department of Oral Maxillofacial Surgery, Academic Medical Center, department of Internal Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient on antiplatelet therapy who has to be treated in the AMC at the Department of Oral and Maxillofacial surgery; 2. Approval of the prescribing physician; 3. At least 18 years old.

Exclusion criteria

Exclusion criteria: 1. Known coagulation defect; 2. Use of oral anticoagulant treatment (vitamin K antagonists) or therapeutic heparin; 3. Severe kidney dysfunction (creatinin clearance < 20 ml/min) or hepatic dysfunction; 4. Unstable coronary artery disease; 5. Patients younger than 18 years of age; 6. Refusal to provide informed consent; 7. Recent placement of a coronary stent (during the last 6 month).

Design outcomes

Secondary

MeasureTime frame
Secondary outcome is the occurrence of thrombo-embolic events at 30 days follow-up. The predictive effect of measurements in DNA, blood and saliva on peri-procedural hemostasis and blood loss is also a secondary endpoint.

Primary

MeasureTime frame
The primary outcome of the study is peri-procedural blood loss.

Contacts

Public ContactM.H. Frank

Academic Medical Center (AMC), Department of Oral- and Maxillofacial Surgery, P.O. Box 22660

m.h.frank@amc.uva.nl+31 (0)20 5662300

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)