asthma Dutch: astma
Conditions
Interventions
four times spirometry, one time with the inhalation of 200ugr salbutamol in the standard body posture, one time 200ugr salbutamol in the forward leaning body posture with the head flexed backwards and
Sponsors
Medisch Spectrum Twente, Enschede
Eligibility
Inclusion criteria
Inclusion criteria: - Clinical history of asthma symptoms. - Age 6 till 16 years old. - Ability to perform reproducible pulmonary function tests, i.e. coefficient of the predicted value variation in 3 of 5 consecutive measurements < 5%.
Exclusion criteria
Exclusion criteria: - Exacerbation in the last 4 weeks prior to the study (hospital admission or use of systemic corticosteroids). - Use of long acting bronchodilators 24 hours before testing. - Use of short acting bronchodilators 8 hours before testing. - Use of leukotriene antagonists 24 hours before testing. - Other pulmonary or cardiac disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1, VC, PEF, MEF25 and MEF75 reversibility (%) | — |
Secondary
| Measure | Time frame |
|---|---|
| Possible discomfort body posture measured with VAS scores Possible side effects of the salbutamol inhalation: number of children complaining about palpitations, tremor, discomfort or rash. | — |
Contacts
Public ContactR. Visser
Medisch Spectrum Twente Departement of pediatrics Haaksbergerstraat 55
Outcome results
None listed