Blink reflex, oxygen, oxygen therapy, cluster headache. Blink reflex, zuurstof, zuurstofbehandeling, clusterhoofdpijn
Conditions
Interventions
100% oxygen at 12 L/min, will be given 3 min. after cluster headache attack onset for 15 min. Blink reflexes will be measured directly after cluster headache attack onset and after 12 min. of oxygen t
Sponsors
Dept. of Neurology, Atrium Medical Centre, Heerlen
Eligibility
Inclusion criteria
Inclusion criteria: 1. Episodic / chronic cluster headache according to ICHD-II criteria, diagnosed by neurologist; 2. Episodic cluster headache patients have to be in cluster period; 3. Age 18-70 years.
Exclusion criteria
Exclusion criteria: 1. Secondary cluster headache, as diagnosed by patient’s neurologist; 2. Other painful conditions which could interfere with patient’s pain perception; 3. Pregnancy or lactation; 4. COPD and other contraindications for oxygen; 5. Intolerability of oxygen face mask; 6. Rebound cluster headache following oxygen therapy; 7. Previous surgical treatment of trigeminal nerve or thermolesion of sphenopalatine ganglion; 8. Side change of cluster headache in previous year; 9. Incapacitation to understand and sign for informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in R2 parameters measured on both sides between time points: Before cluster headache (CH) attack, immediately after CH attack onset and after 12-15 min. of oxygen treatment for CH attack. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Differences in change of R2 parameters in 12-15 min. of oxygen treatment between groups clear responders and non-responders plus moderate responders; 2. Differences in R2 parameters at the aforementioned 3 time points between symptomatic and asymptomatic side; 3. Differences in R2 parameters before a cluster headache attack without and with oxygen treatment. | — |
Contacts
Public ContactP.J. Koehler
Atrium medisch centrum Department of neurology PO Box 4446
Outcome results
None listed